there are several dna proof-reading genes that code for proteins to find and repair damaged dna. what might happen if one of these genes malfunctions?

Answers

Answer 1

Gene malfunctioning leads to genomic instability, apoptosis, or senescence.

What is proofreading?

DNA polymerases are the enzymes that build DNA in cells. During DNA replication (copying), most DNA polymerases can “check their work” with each base that they add. This process is called proofreading. If the polymerase detects that a wrong (incorrectly paired) nucleotide has been added, it will remove and replace the nucleotide right away, before continuing with DNA synthesis.

Proofreading corrects the majority of errors, but a few slip through. Mismatch repair occurs immediately after fresh DNA is synthesized; its function is to delete and replace mispaired nucleotides (ones that were not fixed during proofreading). Mismatch repair can also detect and correct minor insertions and deletions caused by polymerases "slipping" and losing their footing on the template.

Repair processes that help fix damaged DNA include:  

Direct reversalExcision repairExcision repair

Hence, gene malfunctioning leads to genomic instability, apoptosis, or senescence.

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Related Questions

scientists have confirmed by carbon dating that seeds dormant for up to 2000 years can successfully germinate. based on the requirements for germination, what research expedition should you join in order to retrieve some ancient but viable seeds?

Answers

(D) "A trip to the arid Dead Sea region, where your historian colleagues have found a storeroom of wax-sealed jars." is the research expedition should you join in order to retrieve some ancient but viable seeds.

The Dead Sea Scrolls were initially found in 1947 by Bedouin shepherds at Qumran in a lonely maze of caves. The Bedouin found several antique clay jars that had been wax-sealed. They still remain shrouded in mystery and contain biblical and other religious writings that were copied more than 2000 years ago and therefore is accurate to the carbon dating that seeds dormant for up to 2000 years can successfully germinate.

Between 1947 and 1956, the texts were found in 11 caves adjacent to Qumran. Few well-preserved scrolls, which typically only survive in fragments, were discovered in cylindrical jars, but many other neighboring caves yielded identical jars and lids without scrolls.

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Question correction:

Scientists have confirmed by carbon dating that seeds dormant for up to 2000 years can successfully germinate. Based on the requirements for germination, what research expedition should you join in order to retrieve some ancient but viable seeds?

A. A trip to Indonesia, where the civet cat eats and expels coffee beans, producing a gourmet coffee known as Kopi Luwak.

B. A trip to the Irish marsh, where wet peat creates anaerobic conditions, and your colleagues hope to unearth a bog mummy.

C. A trip to the Burgess Shale in Canada, where your paleontologist colleagues have found fossils from the Cambrian era.

D. A trip to the arid Dead Sea region, where your historian colleagues have found a storeroom of wax-sealed jars

Smooth muscle forms rings called ___________ that are usually contracted but relax periodically to allow substances to pass through them.

Answers

Smooth muscle forms ring called sphincters that are usually contracted but relax periodically to allow substances to pass through them.

A sphincter is a circular muscle that normally constricts a body channel or opening and opens when required for normal physiological function. There are sphincters in many species.

The human body contains more than 60 different varieties, some of which are minuscule in size, including the numerous precapillary sphincters. At death, sphincters loosen, frequently leaking fluids and feces.

Every sphincter has a connection to the lumen (opening) that it is enclosing. The lumen is narrowed and the sphincter muscle's length is reduced while it is contracted (closed). The muscle lengthens as a result of relaxation, allowing liquids, solids, or gases to pass through.

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What trait separates the ray finned fish and amphibians

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The traits that separate ray-finned fish and amphibians is: swim-bladder, bony scales and lungs.

Swim-bladder is a large sac-like organ present only in ray-finned fish (bony fishes in general). It is a buoyant structure that enables the fish to swim across water. No such bladder is present in the body of amphibians.

Apart from swim-bladder, the fish also consists of bony scales that act as a protective organ upon the surface of fishes. However the outer surface of the skin of amphibians is slimy in texture. Also the fishes breathe only through gills, whereas the amphibians may have gills, lungs or even skin for respiration.

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please help im timed

Answers

Answer:

Elements with the same number of valence electrons have similar chemical properties.

Explanation:

This is because the valence electron number decides the reactivity and bonding capabilities of an atom.

In a closed ecosystem carbon cannot be produced are used up true or false

Answers

This is where exhaled carbon dioxide and other waste products are effectively converted, either chemically or through photosynthesis, into products such as food, water and oxygen.

What is a closed ecosystem?

Closed systems are characterized as 'self-regenerating' ecosystems that can sustain life without external help. By creating a continuous cycle, all resources can be fully reused.

It is primarily used to describe miniature forms of human-made ecosystems and is of scientific interest. These ecosystems tend to show great potential, especially in establishing life support systems during spaceflights and on space stations, and even in creating space habitats.

In closed ecosystems, it is important to naturally include at least one autotroph, since almost all designed closed ecosystems are based on autotrophs such as green algae. It is also important that all forms of waste produced by one organism are utilized by other organisms within a closed ecosystem.

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During photosynthesis in a eukaryotic cell, an electrochemical gradient is formed across the ___________.

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During photosynthesis in a eukaryotic cell, an electrochemical gradient is formed across the Thylakoid space.

What is Thylakoid space ?

             The thylakoid space is the area inside the thylakoid. A thylakoid is a membrane-bound disc found in plant chloroplasts. The thylakoid membrane contains enzymes required for photosynthesis's light-dependent reactions. During photosynthesis, an electrochemical gradient or proton motive force is created by the release (photolysis) or movement of protons from the stroma into the thylakoid lumen. The energy released during this movement is used by ATP synthase, CF o, and CF1 particles to form ATP mole.

            Inside chloroplasts and cyanobacteria, thylakoids are membrane-bound compartments. They are the site of photosynthesis's light-dependent reactions. Thylakoids are made up of a thylakoid membrane that surrounds a thylakoid lumen. Chloroplast thylakoids frequently form grana, which are stacks of discs. Grana are linked together by intergranal/stromal thylakoids, which connect granum stacks as a single functional compartment. Chlorophyll pigments are found in packets called quantasomes in thylakoid membranes. Each quantasome has between 230 and 250 chlorophyll molecules.

           The thylakoid membrane is the site of photosynthesis's light-dependent reactions, with photosynthetic pigments embedded directly in the membrane. It is an alternating pattern of dark and light bands 1 nanometre in width. The thylakoid lipid bilayer is similar to prokaryotic membranes and the inner chloroplast membrane.

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During photosynthesis in a eukaryotic cell, an electrochemical gradient is formed across the _Thylakoid membrane in the mitochondria_.

An ion that may flow across a membrane typically exhibits an electrochemical gradient, which is a gradient in electrochemical potential. The gradient is made up of two components: an electrical gradient and a chemical gradient, or a difference in charge across a membrane and solute concentration, respectively. What is the Thylakoid membrane?In chloroplasts and cyanobacteria, the light-dependent photosynthesis processes occur in thylakoids, which are membrane-bound structures that resemble sheets. Chlorophyll, which is present there and used to absorb light and utilize it for biological processes, is where it is found. Thylakoid is short for the pouch and has the -oid ending.Lamellae, another name for thylakoids, can also refer to the part of a thylakoid that joins grana.The water photolysis, electron transport chain, and ATP synthesis processes are all carried out in the thylakoid.The thylakoid membrane is the location of the light-dependent processes in photosynthesis because it contains photosynthetic pigments (such as chlorophyll). With a large surface area to volume ratio due to the stacked coil form of the grana, photosynthesis is made more efficient.

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Write a paragraph explaining how nucleic acids and proteins work together to provide instructions for the structures and functions of an organism.

Answers

Answer:

Nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), carry genetic information which is read in cells to make the RNA and proteins by which living things function. The well-known structure of the DNA double helix allows this information to be copied and passed on to the next generation.

Explanation: i know.

Answer:

The nucleic acids contain the instructions for everything else on what to do, they go to the proteins and then kind of mix, they then go throughout the cell feeding it, along with giving the instructions.

Explanation:

sea stars prefer to eat mussels. if sea stars aren't present, mussels outcompete most other species in the mid-intertidal and lessen biodiversity. sea stars are: sea stars prefer to eat mussels. if sea stars aren't present, mussels outcompete most other species in the mid-intertidal and lessen biodiversity. sea stars are: a community dominant. a keystone species. a weak competitor. a competitive dominant.

Answers

If sea stars are not present, then this causes the biodiversity to lessen, hence sea stars are a) keystone species.

In ecology, a keystone species can be described as a species that significantly impacts a particular ecosystem. The presence or absence of a keystone species can affect the entire biodiversity of an ecosystem.

In the case above, sea stars are the keystone species of the mid-intertidal ecosystem as they help to keep the biodiversity in check in that particular ecosystem. Removal of sea stars from this ecosystem causes mussels to increase and lessen the whole biodiversity. As the removal of sea stars is impacting the whole mid-intertidal ecosystem, hence sea stars are the keystone species.

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during photophosphorylation, the ph of the thylakoid interior will be a) higher than the ph of stroma since protons move into thylakoid b) lower than the ph of stroma since protons move into thylakoid space. c) same as the the ph of stroma since protons go in and out of thylakoid space

Answers

Lower than the ph of stroma since protons move into thylakoid space

What is photophosphorylation ?

By activating PSII with the help of solar energy, photophosphorylation transforms ADP into ATP. This involves a procedure known as photolysis, which involves splitting the water molecule into oxygen and hydrogen protons (H+). After then, water and PSI are continuously connected by a single-direction flow of electrons.

Actively moving protons from the stroma to the thylakoid lumen requires energy from an electron transport chain. Consequently, the lumen has a lower pH than the stroma and a substantially larger proton concentration.

Using light energy from photosynthesis, ADP is converted to ATP through the process of photophosphorylation. It involves adding a phosphate group to an ADP molecule in the presence of light in order to create energy-dense ATP molecules.

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predict the following gene and genotypic frequencies for a gene at hardy-weinberg equilibrium within a population of animals where the gene frequency of the dominant allele is 0.9. assume two alleles exist for the gene within the population.

Answers

The predicted genotypic frequencies for an allele of gene at hardy-weinberg equilibrium within a population of animals where the gene frequency of the dominant allele is 0.9 is 0.18

Using the data supplied in the question,

Frequency of allele P = 0.9 or 90%,

Frequency of allele p = 0.1 or 10%.

From Hardy-Weinberg equilibrium : (p^2 + 2pq + q^2)

2pq (Heterozygous genotype) = 2 x 0.9 x 0.1 = 0.18 or 18%

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meiosis is a continous process but we can think of it as taking place in two stages meiosis i and meiosis ii. describe the products of each stage. how do the product

Answers

A reduction division and an equatorial division make up meiosis. To create gametes, meiosis I and meiosis II are necessary.

Meiosis II resembles a mitotic division, whereas meiosis I is a special cell division that only happens in germ cells. Meiosis, which decreases chromosome counts from diploid to haploid, and conjugation (fertilisation), which restores the diploid state by joining two haploid cells, are the two opposing processes that make up this. Chromosome segregation and recombination are the two processes that meiosis uses to create variety. As in mitosis, sister chromatids (the two halves of a duplicated chromosome) still need to be separated. The homologous chromosomes, which an organism acquires from both of its parents and are similar but not identical, must also be separated.

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which of these lines of evidence would not be used by a biologist to determine the relationship between two organisms?

Answers

Answer:put in the comments the options.

Explanation:

On the periodic table lithium and beryllium are in different groups which statement describes why the two elements are in different groups.

They have different number of electron shells.

They have different atomic numbers

They are different colors

They have a different number of electrons in their outer shell

Answers

Answer:

They have a different number of electrons in their outer shell

Which of the following are true in PROKARYOTIC cells?
have ribosomes
small and simple
first cells, prefix meaning "before," thought to be early cells
have a cell membrane
large and complex
have DNA
have organelles and nucleus
no nucleus or membrane bound organelles

Answers

Answer:

prokaryotic cells don't have nucleus or membrane bound organelles

as the human population has increased, the result on natural capital has been . group of answer choices increasing the use of net primary production by humans increasing biodiversity decrease in waste production increasing available renewable resources. increasing natural predators

Answers

As the human population has increased, the result on natural capital has been  increasing the use of net primary production by humans.

A growing population increases the need for resources such as food, water, housing, energy, healthcare, transportation, and more. And all that consumption increases the chance of catastrophic events like pandemics as well as ecological degradation, wars, and other social problems. Rapid development has resulted in unchecked urbanization, which has led to issues including overcrowding, poverty, crime, pollution, and political unrest. It promotes income inequality, slows the rate of GDP growth by keeping levels of capital investment and savings low, puts pressure on agricultural production and land, and worsens unemployment. Economic growth can result from an increasing population. Because more people can generate more things, population expansion will result in economic growth. Higher tax receipts will allow for the funding of public services including health care and environmental initiatives.

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which of the following statements is NOT part of the cell theory A. cells can absorb food and oxygen B. cells are basic units of structure and function in living things C. All cells are produced from other cells D. All living things are composed of cells

Answers

Answer: A. cells can absorb food and oxygen

Curare is a plant extract used by indigenous tribes in central and south america as a paralyses poison for hunting. Curare binds to ach receptors, but does not open the associated channels. What process in the motor unit is affected by curare? how would this affect muscle contraction?.

Answers

It is widely used to suppress neuromuscular junction activation. At useful concentrations, curare can decrease muscle contraction without compromising mental function, else, it is lethal.

What is Curare?

The first anesthetic paralytic, curare (also known as D-tubocurare), has been supplanted by more recent medications. Around 1940, it was added to anesthesia.

It is taken from the Strychnos toxifera plant. The term "curare" refers to a variety of plant-based alkaloid arrow poisons used by native populations in Central and South America. Curare, which is used as a paralyzing agent for hunting and medicinal purposes, only becomes active when directly contaminated by a poison dart or arrow or when administered intravenously.

Curare can cause serious bodily injury if consumed. A neurotransmitter called acetylcholine may be inhibited, and abnormal muscular relaxation may lead to muscle paralysis.

Curare weakens or paralyzes skeletal muscles by interfering with the passage of nerve impulses between the nerve axon and the mechanism of muscle cell contraction, according to study.

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2. Hoag hopes that Dr. Potbury will inform him that the substance under his
fingernails is blood. When he is informed that this is not the circumstance, he is
desperate to know its true nature. Speculate as to what it could possibly be.
|

Answers

Robert A. Heinlein's "The Unpleasant Profession Of Jonathan Hoag"– things do not end nicely.due to an excessive passion of life,With fear and hope freed free,In a simple prayer of thanks, we thank.

Describe" unpleasant profession of Hoag"

Ted awakens to discover Cynthia seemingly in a coma.He covers every mirror in the apartment with paint after realizing that the dreams were accurate.The only physician he knows, Potbury, is immediately called to come see Cynthia.When Ted repeats the Sons of the Bird's catchphrase, "The Bird is Cruel!" to Potbury, he obsessively conceals his face, just like the Sons did. Potbury diagnoses her with lethargica gravis.Ted overpowers Potbury after realizing he is one of them and imprisons him in the restroom.Hoag answers the phone and arrives at the residence.Hoag claims that lethargica gravis is simply another name for "deep sleep" when told about Potbury.When they open the bathroom door, they discover Potbury is no longer there. He gives them a list of items to bring and departs, leaving them rather perplexed. Ted and Cynthia find Hoag there after arriving at the park with the fine dishes and wines he ordered.They enjoy an epicurean picnic while Hoag reveals that he is an art critic.Their entire world was conceptualized by a "artist" as a school project.In order to evaluate the experiences, critics live as regular people in the world without realizing they are critics.As Hoag notes, one such experience is eating and drinking, since the basic act of obtaining energy to survive had not previously been considered to be a "experience".Another is sex, which is initially dismissed as absurd before Hoag discovers that it forms the cornerstone of "the tragedy of human love" that he observes between two people. Ted and Cynthia have seen everything, including Hoag during the daytime, and it was all caused by the Sons of the Bird.

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which objects on earth absorb photons, what is it reflected as?

Answers

In the photoelectric effect process, photon loses its entire energy to an atomic electron which is in turn released from the atom.

When a photon is absorbed by an electron it itself get destroyed, but it's energy is transferred into the atoms of the object it hit. That energy may re-emitted as a another photon and it happens when light reflects off an object.

Materials like Coal, black paint, and carbon nanotube arrays absorbs light and materials, such as glass , have no absorbing properties and therefore they look transparent. Photon enters the eye get absorbed by one of the rod or cone cells that envelop the retina on the inner back surface of the eye.

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The ability to detect whether your body is in a horizontal or vertical position depends most directly on.

Answers

Answer: the vestibular sense

Explanation:

The ability to detect whether your body is in a horizontal or vertical position depends most directly on (accommodation, sensory adaptation, the vestibular sense, olfactory receptors, subliminal stimulation) While playing tennis, you need to know where your limbs are located so you can move them into right positions or swing your racket.

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What do scientists think were the first eukaryotic organisms on Earth?
euglena
paramecium
plasmodium
amoeba

Answers

According to the given information euglena were the first eukaryotic organisms on Earth.

What organism is eukaryotic?

Eukaryotes are organisms whose cells have membrane-bound organelles in addition to a nucleus. Eukaryotic organisms come in a wide variety, along with most algae, all mammals, vegetation, fungus, and protists. Eukaryotes can have a single cell or many cells. They are referred to as the "powerhouse of the cell" because they generate energy (ATP). helps to control the metabolism of cells.

What five eukaryotic organisms are examples?

Humans, fungi, protists, and plants are eukaryotes cell examples. They have chromosomes, which organize the genetic material. Eukaryotic have the Golgi, mitochondrial, golgi apparatus, and nucleus. Let's look more closely at the elements of eukaryotic cells.

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in which way(s) are dendrites and axons similar? a both are characterized by branching. b they have similar lengths. c both exhibit a tapering of diameter with increasing distance from the cell body. d all of the above

Answers

Dendrites and Axon both have branching as a defining feature.

What are axons and what do they do?

Your brain's neurons each have a solitary, lengthy cable that extends from the cell's center. A neuron's axon, a cable that is far thinner than a human hair, is where electrical impulses escape the cell to be picked up by nearby neurons.

Explain dendrites.

Extensions called dendrites are designed to pick up messages from neighboring cells. When activated by other neurons, they take the shape of projections with a tree-like structure that transport the electrochemical charge to the cell body (or, more rarely, directly to the axons).

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A multicellular organism has 20 (2n) chromosomes in its body cells. How many chromosomes are in the
haploid (n) gametes

Answers

23 chromosomes


Explanation:

in 1960 the united states had 16,000 km of interstate highways today the interstate high way system includes 77,000 km of paved roadways what percent does this represent

Answers

In 1960 the united states had 16,000 km of interstate highways today the interstate high way system includes 77,000 km of paved roadways. This represents the total increase of 38 % is shown in the data. Thus, option C is correct.

What is clinical support?

The term clinical support has been defined as the model which has been arranged in such a manner that has been facilitated, contrast communication channel for everyone who does clinical activity with the patients. Clinical support has been much needed for the patients.

The practice of the clinical support has been performed by the clinical support worker and they perform their role very seriously to serve the patient because for them everything is patient's good health.

Therefore, In 1960 the united states had 16,000 km of interstate highways today the interstate high way system includes 77,000 km of paved roadways. This represents the total increase of 38 % is shown in the data. Thus, option C is correct.

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Nitrification reactions carried out be bacteria as part of the nitrogen cycle cn be considered.

Answers

Nitrification reactions carried out by bacteria as part of the nitrogen cycle can be considered as nitrogen fixation.

The first phase in the nitrogen cycle is nitrogen fixation, which involves turning atmospheric nitrogen into ammonia. The second step, nitrification, involves turning ammonia into nitrates and nitrates.

What are Nitrification reactions?

The biological oxidation of ammonia to nitrite and subsequent oxidation of the nitrite to nitrate by different species is known as nitrification alternatively, comammox bacteria may directly oxidize ammonia to nitrate. The rate-limiting phase in nitrification is often the conversion of ammonia to nitrite. The nitrogen cycle in the soil goes through an essential stage called nitrification. Small populations of autotrophic bacteria and archaea carry out the aerobic nitrification process.

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please help

how does the Smooth Endoplasmic Reticulum function work in a plant cell

4-5 sentences

thank you

Answers

Answer:

The endoplasmic reticulum can either be smooth or rough, and in general its function is to produce proteins for the rest of the cell to function. The rough endoplasmic reticulum has on it ribosomes, which are small, round organelles whose function it is to make those proteins.

What is the major non-covalent interaction that holds two strands together in a double helix?.

Answers

Answer:

Hydrogen bonds

Explanation:

What is the major non covalent interaction that holds two strands together in a double helix? The hydrogen bonds between the base pairs form the double helical structure of DNA. There is no exchange or sharing of electrons in hydrogen bonds as seen in covalent or ionic bonds.

scottish and amazonian legends both tell of beautiful men and women that break the hearts of their lovers when they eventually must return to their true form, an aquatic mammal. quizlet

Answers

False; both scottish and amazonian legends depict attractive people who shatter their lovers' hearts by returning to their true natures as aquatic mammals.

Mammary glands, which in females produce milk for nourishing (nursing) their young, a neocortex (a portion of the brain), fur or hair, and three middle ear bones are features that distinguish mammals (from the Latin mamma, "breast") from other vertebrate creatures. With the exception of birds, from which they split around 300 million years ago in the Carboniferous, they are distinguished by these traits from reptiles (including other birds). A total of 29 orders and 6,400 described mammals specie are currently living. Rodents, bats, and Eulipotyphla are the greatest orders in terms of the number of species (hedgehogs, moles, shrews, and others). The Artiodactyla, which includes cetaceans and even-toed ungulates, and the Carnivora are the following three groups: Primates (which includes humans, apes, monkeys, and other species), and (cats, dogs, and seals)

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When there is a cut in the skin and bacteria enter the body, the immune system responds. First, macrophages approach the area of the cut. Next, the macrophages surround any bacterial cells and engulf them. What feature of the immune system is best described by this scenario?
A.
self-recognition, which is a part of adaptive immunity
B.
the phagocytotic barrier, which is a part of innate immunity
C.
antigen specificity, which is a part of adaptive immunity
D.
the inflammatory barrier, which is a part of innate immunity

Answers

The feature of the immune system which is best described by this scenario which involves engulfing of bacterial cells is the phagocytotic barrier, which is a part of innate immunity and is denoted as option B.

What is Immune system?

This is part of the body which is responsible for protection and helps to fight germs and diseases through the white blood cells which are present in the body system.

The immune system comprises of macrophages which engulfs the pathogen through the process known as phagocytosis which is why phagocytotic barrier which is a part of innate immunity was chosen as the correct choice.

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The locations for three genes have been added to this cartoon. For clarity, the locations have only been noted on one chromatid. The lowest frequency of crossovers would occur between genes ____ and ____.

Answers

The lowest frequency of crossovers would occur between genes a and b (the genes closet to one another on a chromosome)

The exchange of genetic material between the non-sister chromatids of two homologous chromosomes during sexual reproduction, or chromosomal crossover, leads to recombinant chromosomes. It is one of the last stages of genetic recombination, which takes place during the synapsis process at the pachytene stage of prophase I of meiosis. Before the synaptonemal complex forms, synapsis starts, and it doesn't stop until close to prophase I's conclusion.

The distance between genes is directly inversely correlated with the probability of gene crossing over between two genes that are located on the same chromosome (linked gene). Unlinked genes are assorted independently during cell division when two genes are not found on the same chromosome. Therefore, crossing over occurs frequently.

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